Biochemistry
Tenth Edition ©2023 Jeremy Berg; Gregory Gatto Jr.; Justin Hines; John L. Tymoczko; Lubert Stryer Formats: Achieve, Achieve Essentials, E-book, Print
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Authors
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Jeremy M. Berg
Jeremy M. Berg received his B.S. and M.S. degrees in Chemistry from Stanford University (where he did research with Keith Hodgson and Lubert Stryer) and his PhD in Chemistry from Harvard with Richard Holm. He then completed a postdoctoral fellowship with Carl Pabo in Biophysics at Johns Hopkins University School of Medicine. He was an Assistant Professor in the Department of Chemistry at Johns Hopkins from 1986 to 1990. He then moved to Johns Hopkins University SÂchool of Medicine as Professor and Director of the Department of Biophysics and Biophysical Chemistry, where he remained until 2003. He then became Director of the National Institute of General Medical Sciences at the National Institutes of Health. In 2011, he moved to the University of Pittsburgh, where he is now Professor of Computational and Systems Biology and Pittsburgh Foundation Chair and Director of the Institute for Personalized Medicine. He served as President of the American Society for Biochemistry and Molecular Biology from 2011 to 2013 and as Editor-in-Chief for Science magazine and the Science family of journals from 2016 to 2019. Dr. Berg has received numerous awards for his research, teaching, and public service. He is an elected member of the National Academy of Medicine and the American Academy of Arts and Sciences. He is coauthor, with Stephen J. Lippard, of the textbook Principles of Bioinorganic Chemistry. He greatly enjoys sharing his life with his wife, three grown children, and grandchildren.
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Gregory J. Gatto, Jr.
Gregory J. Gatto, Jr., received his A.B. degree in Chemistry from Princeton University, where he worked with Martin F. Semmelhack and was awarded the Everett S. Wallis Prize in Organic Chemistry. In 2003, he received his MD and PhD degrees from the Johns Hopkins University School of Medicine, where he studied the structural biology of peroxisomal targeting signal recognition with Dr. Berg and received the Michael A. Shanoff Young Investigator Research Award. He completed a postdoctoral fellowship in 2006 with Christopher T. Walsh at Harvard Medical School, where he studied the biosynthesis of the macrolide immunosuppressants. Dr. Gatto is currently a Scientific Director in the Novel Human Genetics Research Unit at GlaxoSmithKline. While he enjoys losing at board games, attempting but not completing crossword puzzles, and watching baseball games at every available opportunity, he treasures most the time he spends with his wife Megan and sons Timothy and Mark.
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Justin Hines
Justin K. Hines is Professor of Chemistry at Lafayette College, where he teaches general chemistry and biochemistry courses and conducts education and NIH-funded laboratory research on protein misfolding with undergraduates. He received both his B.S. and PhD in Biochemistry from Iowa State University, where he studied the structure and regulation of the enzymes of central metabolism with Richard B. Honzatko and Herbert J. Fromm. He then completed a postdoctoral fellowship with Elizabeth A. Craig in Biochemistry at the University of Wisconsin–Madison. Professor Hines has won numerous awards for teaching and research, including being named a Cottrell Scholar by the Research Corporation for Science Advancement and a Henry-Dreyfus Teacher-Scholar by the Camille and Henry Dreyfus Foundation. He is also the author of the case-studies series for Macmillan’s three biochemistry textbooks. He enjoys running, hiking, games of any kind, and spending time with his wife and children.
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John L. Tymoczko
John L. Tymoczko was Towsley Professor of Biology Emeritus at Carleton College, where he taught from 1976 until his death in 2019. He taught a variety of courses, including Biochemistry, Biochemistry Laboratory, Oncogenes and the Molecular Biology of Cancer, and Exercise Biochemistry, and cotaught an introductory course, Energy Flow in Biological Systems. Professor Tymoczko received his B.A. from the University of Chicago in 1970 and his PhD in Biochemistry from the University of Chicago with Shutsung Liao at the Ben May Institute for Cancer Research. He then had a postdoctoral position with Hewson Swift of the Department of Biology at the University of Chicago. The focus of his research was on steroid receptors, ribonucleoprotein particles, and proteolytic processing enzymes.
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Lubert Stryer
Lubert Stryer is Winzer Professor of Cell Biology, Emeritus, in the School of Medicine and Professor of Neurobiology, Emeritus, at Stanford University, where he has been on the faculty since 1976. He received his MD from Harvard Medical School. Professor Stryer has received many awards for his research on the interplay of light and life, including the Eli Lilly Award for Fundamental Research in Biological Chemistry, the Distinguished Inventors Award of the Intellectual Property Owners’ Association, and election to the National Academy of Sciences and the American Philosophical Society. He was awarded the National Medal of Science in 2006. The publication of his first edition of Biochemistry in 1975 transformed the teaching of biochemistry.
Table of Contents
2 Protein Composition and Structure
3 Binding and Molecular Recognition
4 Protein Methods
5 Enzymes: Core Concepts and Kinetics
6 Enzyme Catalytic Strategies
7 Enzyme Regulatory Strategies
8 DNA, RNA, and the Flow of Genetic Information
9 Nucleic Acid Methods
10 Exploring Evolution and Bioinformatics
11 Carbohydrates and Glycoproteins
12 Lipids and Biological Membranes
13 Membrane Channels and Pumps
14 Signal-Transduction Pathways
15 Metabolism: Basic Concepts and Themes
16 Glycolysis and Gluconeogenesis
17 Pyruvate Dehydrogenase and the Citric Acid Cycle
18 Oxidative Phosphorylation
19 Phototrophy and the Light Reactions of Photosynthesis
20 The Calvin–Benson Cycle and the Pentose Phosphate Pathway
21 Glycogen Metabolism
22 Fatty Acid and Triacylglycerol Metabolism
23 Protein Turnover and Amino Acid Catabolism
24 Integration of Energy Metabolism
25 Biosynthesis of Amino Acids
26 Nucleotide Biosynthesis
27 Biosynthesis of Membrane Lipids and Steroids
28 DNA Replication, Repair, and Recombination
29 RNA Functions, Biosynthesis, and Processing
30 Protein Biosynthesis
31 Control of Gene Expression
32 Principles of Drug Discovery and Development
Product Updates
Chapter content has been thoughtfully revised around the themes of evolutionary perspective, clinical applications and physiological relevance, biotechnological and industrial applications, and NEW! the importance of time and time scales. For example:
- NEW! Chapter 3 focuses on molecular recognition
- Updated and new discussions with clinical and physiological applications, such as anticoagulant medicines (chapter 7), metabolism and cancer (chapter 24), and drug discovery (chapter 32)
- Updated and new illustrations
- NEW! Problem-solving techniques and practice throughout the text and online, such as:
- NEW! Self-check questions and worked examples
- NEW in Achieve! Every end-of-chapter now assignable online with autograding, answer-specific feedback, and worked solutions
- NEW in Achieve! Skills You Need Activities for each chapter reinforce skills and concepts from prerequisite courses
- NEW in Achieve! iClicker activities and free integration with iClicker
- NEW in Achieve! In-Class Activities for Problem Solving with Instructor Activity Guides and Student Worksheets
- NEW! Scientist Profiles illustrating the wide range of backgrounds, training, and careers that lead to many important contributions in biochemistry.
Authors
-
Jeremy M. Berg
Jeremy M. Berg received his B.S. and M.S. degrees in Chemistry from Stanford University (where he did research with Keith Hodgson and Lubert Stryer) and his PhD in Chemistry from Harvard with Richard Holm. He then completed a postdoctoral fellowship with Carl Pabo in Biophysics at Johns Hopkins University School of Medicine. He was an Assistant Professor in the Department of Chemistry at Johns Hopkins from 1986 to 1990. He then moved to Johns Hopkins University SÂchool of Medicine as Professor and Director of the Department of Biophysics and Biophysical Chemistry, where he remained until 2003. He then became Director of the National Institute of General Medical Sciences at the National Institutes of Health. In 2011, he moved to the University of Pittsburgh, where he is now Professor of Computational and Systems Biology and Pittsburgh Foundation Chair and Director of the Institute for Personalized Medicine. He served as President of the American Society for Biochemistry and Molecular Biology from 2011 to 2013 and as Editor-in-Chief for Science magazine and the Science family of journals from 2016 to 2019. Dr. Berg has received numerous awards for his research, teaching, and public service. He is an elected member of the National Academy of Medicine and the American Academy of Arts and Sciences. He is coauthor, with Stephen J. Lippard, of the textbook Principles of Bioinorganic Chemistry. He greatly enjoys sharing his life with his wife, three grown children, and grandchildren.
-
Gregory J. Gatto, Jr.
Gregory J. Gatto, Jr., received his A.B. degree in Chemistry from Princeton University, where he worked with Martin F. Semmelhack and was awarded the Everett S. Wallis Prize in Organic Chemistry. In 2003, he received his MD and PhD degrees from the Johns Hopkins University School of Medicine, where he studied the structural biology of peroxisomal targeting signal recognition with Dr. Berg and received the Michael A. Shanoff Young Investigator Research Award. He completed a postdoctoral fellowship in 2006 with Christopher T. Walsh at Harvard Medical School, where he studied the biosynthesis of the macrolide immunosuppressants. Dr. Gatto is currently a Scientific Director in the Novel Human Genetics Research Unit at GlaxoSmithKline. While he enjoys losing at board games, attempting but not completing crossword puzzles, and watching baseball games at every available opportunity, he treasures most the time he spends with his wife Megan and sons Timothy and Mark.
-
Justin Hines
Justin K. Hines is Professor of Chemistry at Lafayette College, where he teaches general chemistry and biochemistry courses and conducts education and NIH-funded laboratory research on protein misfolding with undergraduates. He received both his B.S. and PhD in Biochemistry from Iowa State University, where he studied the structure and regulation of the enzymes of central metabolism with Richard B. Honzatko and Herbert J. Fromm. He then completed a postdoctoral fellowship with Elizabeth A. Craig in Biochemistry at the University of Wisconsin–Madison. Professor Hines has won numerous awards for teaching and research, including being named a Cottrell Scholar by the Research Corporation for Science Advancement and a Henry-Dreyfus Teacher-Scholar by the Camille and Henry Dreyfus Foundation. He is also the author of the case-studies series for Macmillan’s three biochemistry textbooks. He enjoys running, hiking, games of any kind, and spending time with his wife and children.
-
John L. Tymoczko
John L. Tymoczko was Towsley Professor of Biology Emeritus at Carleton College, where he taught from 1976 until his death in 2019. He taught a variety of courses, including Biochemistry, Biochemistry Laboratory, Oncogenes and the Molecular Biology of Cancer, and Exercise Biochemistry, and cotaught an introductory course, Energy Flow in Biological Systems. Professor Tymoczko received his B.A. from the University of Chicago in 1970 and his PhD in Biochemistry from the University of Chicago with Shutsung Liao at the Ben May Institute for Cancer Research. He then had a postdoctoral position with Hewson Swift of the Department of Biology at the University of Chicago. The focus of his research was on steroid receptors, ribonucleoprotein particles, and proteolytic processing enzymes.
-
Lubert Stryer
Lubert Stryer is Winzer Professor of Cell Biology, Emeritus, in the School of Medicine and Professor of Neurobiology, Emeritus, at Stanford University, where he has been on the faculty since 1976. He received his MD from Harvard Medical School. Professor Stryer has received many awards for his research on the interplay of light and life, including the Eli Lilly Award for Fundamental Research in Biological Chemistry, the Distinguished Inventors Award of the Intellectual Property Owners’ Association, and election to the National Academy of Sciences and the American Philosophical Society. He was awarded the National Medal of Science in 2006. The publication of his first edition of Biochemistry in 1975 transformed the teaching of biochemistry.
Table of Contents
2 Protein Composition and Structure
3 Binding and Molecular Recognition
4 Protein Methods
5 Enzymes: Core Concepts and Kinetics
6 Enzyme Catalytic Strategies
7 Enzyme Regulatory Strategies
8 DNA, RNA, and the Flow of Genetic Information
9 Nucleic Acid Methods
10 Exploring Evolution and Bioinformatics
11 Carbohydrates and Glycoproteins
12 Lipids and Biological Membranes
13 Membrane Channels and Pumps
14 Signal-Transduction Pathways
15 Metabolism: Basic Concepts and Themes
16 Glycolysis and Gluconeogenesis
17 Pyruvate Dehydrogenase and the Citric Acid Cycle
18 Oxidative Phosphorylation
19 Phototrophy and the Light Reactions of Photosynthesis
20 The Calvin–Benson Cycle and the Pentose Phosphate Pathway
21 Glycogen Metabolism
22 Fatty Acid and Triacylglycerol Metabolism
23 Protein Turnover and Amino Acid Catabolism
24 Integration of Energy Metabolism
25 Biosynthesis of Amino Acids
26 Nucleotide Biosynthesis
27 Biosynthesis of Membrane Lipids and Steroids
28 DNA Replication, Repair, and Recombination
29 RNA Functions, Biosynthesis, and Processing
30 Protein Biosynthesis
31 Control of Gene Expression
32 Principles of Drug Discovery and Development
Product Updates
Chapter content has been thoughtfully revised around the themes of evolutionary perspective, clinical applications and physiological relevance, biotechnological and industrial applications, and NEW! the importance of time and time scales. For example:
- NEW! Chapter 3 focuses on molecular recognition
- Updated and new discussions with clinical and physiological applications, such as anticoagulant medicines (chapter 7), metabolism and cancer (chapter 24), and drug discovery (chapter 32)
- Updated and new illustrations
- NEW! Problem-solving techniques and practice throughout the text and online, such as:
- NEW! Self-check questions and worked examples
- NEW in Achieve! Every end-of-chapter now assignable online with autograding, answer-specific feedback, and worked solutions
- NEW in Achieve! Skills You Need Activities for each chapter reinforce skills and concepts from prerequisite courses
- NEW in Achieve! iClicker activities and free integration with iClicker
- NEW in Achieve! In-Class Activities for Problem Solving with Instructor Activity Guides and Student Worksheets
- NEW! Scientist Profiles illustrating the wide range of backgrounds, training, and careers that lead to many important contributions in biochemistry.
Biochemistry 10e with Achieve builds on over four decades of exceptional writing, clear graphics, coverage of the latest research technique, and its signature emphasis on physiological and medical relevance with new emphasis on the importance of diversity and team work and a focus on problem-solving techniques and skills.
With a new and updated suite of online resources, including hundreds of end-of-chapter problems with answer-specific feedback, activities for in-class and out-of-class, and an emphasis on visualization, Biochemistry with Achieve sets a new standard for biochemistry programs!
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Jeremy Berg; Gregory Gatto Jr.; Justin Hines; John L. Tymoczko; Lubert Stryer | Tenth Edition | ©2023 | ISBN:9781319418083
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Are you a campus bookstore looking for ordering information?
MPS Order Search Tool (MOST) is a web-based purchase order tracking program that allows customers to view and track their purchases. No registration or special codes needed! Just enter your BILL-TO ACCT # and your ZIP CODE to track orders.
Canadian Stores: Please use only the first five digits/letters in your zip code on MOST.
Visit MOST, our online ordering system for booksellers: https://tracking.mpsvirginia.com/Login.aspx
Learn more about our Bookstore programs here: https://www.macmillanlearning.com/college/us/contact-us/booksellers
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Our courses currently integrate with Canvas, Blackboard (Learn and Ultra), Brightspace, D2L, and Moodle. Click on the support documentation below to find out more details about the integration with each LMS.
Integrate Macmillan courses with Blackboard
Integrate Macmillan courses with Canvas
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If you’re a verified instructor, you can request a free sample of our courseware, e-book, or print textbook to consider for use in your courses. Only registered and verified instructors can receive free print and digital samples, and they should not be sold to bookstores or book resellers. If you don't yet have an existing account with Macmillan Learning, it can take up to two business days to verify your status as an instructor. You can request a free sample from the right side of this product page by clicking on the "Request Instructor Sample" button or by contacting your rep. Learn more.
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Sometimes also referred to as a spiral-bound or binder-ready textbook, loose-leaf textbooks are available to purchase. This three-hole punched, unbound version of the book costs less than a hardcover or paperback book.
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Achieve (full course) includes our complete e-book, as well as online quizzing tools, multimedia assets, and iClicker active classroom manager.
Most Achieve Essentials courses do not include our e-books and adaptive quizzing.
Visit our comparison table for details: https://www.macmillanlearning.com/college/us/digital/achieve/compare
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Achieve (full course) includes our complete e-book, as well as online quizzing tools, multimedia assets, and iClicker active classroom manager.
Achieve Read & Practice only includes our e-book and adaptive quizzing, and does not include instructor resources and assignable assessments. Read & Practice does integrate with LMS.
Visit our comparison table for details: https://www.macmillanlearning.com/college/us/digital/achieve/compare
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We can help! Contact your representative to discuss your specific needs for your course. If our off-the-shelf course materials don’t quite hit the mark, we also offer custom solutions made to fit your needs.
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Biochemistry
Biochemistry 10e with Achieve builds on over four decades of exceptional writing, clear graphics, coverage of the latest research technique, and its signature emphasis on physiological and medical relevance with new emphasis on the importance of diversity and team work and a focus on problem-solving techniques and skills.
With a new and updated suite of online resources, including hundreds of end-of-chapter problems with answer-specific feedback, activities for in-class and out-of-class, and an emphasis on visualization, Biochemistry with Achieve sets a new standard for biochemistry programs!
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