Look Inside Look Inside Cover: Molecular Cell Biology, 9th Edition by Harvey Lodish; Arnold Berk; Chris A. Kaiser; Monty Krieger; Anthony Bretscher; Hidde Ploegh; Kelsey C. Martin; Michael Yaffe; Angelika Amon
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Molecular Cell Biology

Ninth Edition ©2021 Harvey Lodish; Arnold Berk; Chris A. Kaiser; Monty Krieger; Anthony Bretscher; Hidde Ploegh; Kelsey C. Martin; Michael Yaffe; Angelika Amon

Available for the first time with Macmillans new online learning tool, Achieve, Molecular Cell Biology remains the most authoritative and cutting-edge resource available for the cell biology course. The author team, consisting of world-class researchers and teachers, inc...

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Look Inside Look Inside Cover: Molecular Cell Biology, 9th Edition by Harvey Lodish; Arnold Berk; Chris A. Kaiser; Monty Krieger; Anthony Bretscher; Hidde Ploegh; Kelsey C. Martin; Michael Yaffe; Angelika Amon

GO DIGITAL WITH ACHIEVE
The authoritative Cell Biology resource, now available with Achieve

Available for the first time with Macmillans new online learning tool, Achieve, Molecular Cell Biology remains the most authoritative and cutting-edge resource available for the cell biology course. The author team, consisting of world-class researchers and teachers, incorporates medically relevant examples where appropriate to help illustrate the connections between cell biology and health and human disease. The emphasis on experimental techniques that drive advances in biomedical sciences teaches students the skills they need for their careers.

Achieve, Macmillan’s new online learning platform, supports educators and students throughout the full range of instruction, including assets suitable for pre-class preparation, in-class active learning, and post-class study and assessment. Featuring new digital resources to engage students and help them to master cell biology concepts, the pairing of a powerful new platform with outstanding biology content provides an unrivaled learning experience.

Features

Now Supported in Achieve
Achieve supports educators and students throughout the full range of instruction, including assets suitable for pre-class preparation, in-class active learning, and post-class study and assessment. The pairing of a powerful new platform with outstanding biology content provides an unrivaled learning experience.

Features of Achieve include:

  • A design guided by learning science research. Co-designed through extensive collaboration and testing by both students and faculty including two levels of Institutional Review Board approval for every study of Achieve
  • A learning path of powerful content including pre-class, in-class, and post-class activities and assessments.
  • A detailed gradebook with insights for just-in-time teaching and reporting on student achievement by learning objective.
  • Easy integration and gradebook sync with iClicker classroom engagement solutions.
  • Simple integration with your campus LMS and availability through Inclusive Access programs.

New media and assessment features in Achieve include:

  • New Smart Biology Animations provide cutting-edge 3D tools for students to help them understand cell biology at a structural level. Based on data from the World Wide Protein Databank, these animations provide students with highly accurate visualizations of structures and processes. Twenty six animations are included in Achieve and include associated assessments that can be assigned and automatically graded. 
  • Eight new In-class activities, along with revised classroom response questions provide support for an active and inclusive classroom.
  • LearningCurve adaptive quizzes provide formative assessments to help students prepare before class.
  • Case Studies and Analyze the Data Problems focus on real world applications.
  • Chapter Concept Quizzes provide easy to assign and automatically graded assessments.

Features of the text include:

  • An approach grounded by emphasis of the experiments that define our understanding of cell biology, engaging students with the exciting breakthroughs that define the field’s history and point to its future.
  • Experimental Figures illustrate real experiments and show real data.
  • Medical and Plant Biology Connections are woven throughout the chapters where appropriate to give students an appreciation for the clinical applications of the basic science they are learning.
  • Key Concepts for each section provide a learning framework for students as they progress through each chapter.

New to This Edition

Now Supported in Achieve
Achieve supports educators and students throughout the full range of instruction, including assets suitable for pre-class preparation, in-class active learning, and post-class study and assessment. The pairing of a powerful new platform with outstanding biology content provides an unrivaled learning experience.

Features of Achieve include:

  • A design guided by learning science research. Co-designed through extensive collaboration and testing by both students and faculty including two levels of Institutional Review Board approval for every study of Achieve
  • A learning path of powerful content including pre-class, in-class, and post-class activities and assessments.
  • A detailed gradebook with insights for just-in-time teaching and reporting on student achievement by learning objective.
  • Easy integration and gradebook sync with iClicker classroom engagement solutions.
  • Simple integration with your campus LMS and availability through Inclusive Access programs.

New media and assessment features in Achieve include:

  • New Smart Biology Animations provide cutting-edge 3D tools for students to help them understand cell biology at a structural level. Based on data from the World Wide Protein Databank, these animations provide students with highly accurate visualizations of structures and processes. Twenty six of these animations are included in Achieve and include associated assessments so that they can be assigned and automatically graded. 
  • Eight New In-class activities, along with revised classroom response questions provide support for an active and inclusive classroom.
  • LearningCurve adaptive quizzes provide formative assessments to help students prepare before class.
  • Case Studies and Analyze the Data Problems focus on real world applications.
  • Chapter Concept Quizzes provide easy to assign and automatically graded assessments.

Updates to the text include:

  • Updated content throughout the text highlight new methodologies and latest research discoveries.
  • New Chapter 21: Responding to the Cellular Environment
    reflects recent developments in cell signaling and  expanded coverage to emphasize new research developments.
  • New co-author Michael Yaffe from MIT is a cancer specialist on the frontlines of COVID19 treatment and research. https://ki.mit.edu/people/faculty/yaffe




"This chapter provides a great overview of what is to come, the selection of pictures are great.  The descriptions of the pictures are awesome.  Another thing I like is that this chapter provides a lot of information and does not rush into the next chapter." -Jamie Parker

"The logic is great. I love it!" -Dou Zhicheng

"I really enjoyed reading the chapter. It flowed nicely and was easy to understand…" -Maianne Poxleitner

"This is an excellent chapter, which provides a concise and informative exposition of techniques referenced in other sections of the text that provide the evidence for our understanding of cell structures and functions.  I believe that all the relevant microscopy techniques and major advances are well covered in this chapter. Other topics such as cell fractionation and analysis and immunological techniques complement material found in other text chapters." -Thomas Keller

"This chapter provides excellent detail on all of the topics covered. Material presented is current and accurate. The key concepts at the end of each section are well written and provide appropriately succinct synopses of the material." -Jamie Siders Sanford

"Well integrated focus on evolution and the why the genome is arranged the way it is - even in cases where answers are somewhat speculative. I really liked this part. I was able to follow the figures demonstrating mechanisms (e.g., transposon copying) without even much reference to the legends - thus I felt these were well done." -Wendy Hanna-Rose

"[C]ell biology without the detail is... high school, not college level - so overall great job. Love the rigor and the discussion." -Philip Santangelo

"1) engagingly written 2) lots of beautiful fluorescence micrographs 3) I liked that the emphasis was on microtubules (a huge literature), rather than all cytoskeletal elements being covered in a single chapter 4) inclusion of experimental approaches that led to a particular finding or model." -Susan Spencer

"1) The art is amazing 2) It is comprehensive 3) It is up-to-date. 4) I really appreciate the section on primary cilium." -Richard Londraville

"The content is definitely well-presented with excellent writing in a student-friendly writing style. The Overview of the Cell Cycle is excellent. The information is told like a story; very effective." -Hao Nguyen

"The cell cycle overview in the beginning sets up the rest of the Chapter quite well. The level of detail between molecular mechanism and cellular processes or behavior of macromolecules throughout the cell cycle is well balanced." -Salil Lachke

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Table of Contents

  1. Molecules, Cells, and Model Organisms
  2. Chemical Foundations
  3. Protein Structure and Function
  4. Culturing and Visualizing Cells
  5. Fundamental Molecular Genetic Mechanisms
  6. Molecular Genetic Techniques
  7. Genes and Genomics
  8. Transcriptional Control of Gene Expression
  9. Post-Transcriptional Gene Control
  10. Biomembrane Structure
  11. Transmembrane Transport of Ions and Small Molecules
  12. Cellular Energetics
  13. Moving Proteins into Membranes and Organelles
  14. Vesicular Traffic, Secretion, and Endocytosis
  15. Cell Signaling I
  16. Growth Factor and Cytokine Signaling
  17. Cell Organization and Movement I
  18. Cell Organization and Movement II
  19. The Eukaryotic Cell Cycle
  20. Integrating Cells into Tissues
  21. Responding to the Cellular Environment
  22. Stem Cells, Cell Asymmetry, and Cell Death
  23. Nerve Cells
  24. Immunology
  25. Cancer
Headshot of Harvey Lodish

Harvey Lodish

HARVEY LODISH is Professor of Biology and Professor of Biological Engineering at the Massachusetts Institute of Technology and a Founding Member of the Whitehead Institute for Biomedical Research. Dr. Lodish is also a member of the National Academy of Sciences and the American Academy of Arts and Sciences and was President (2004) of the American Society for Cell Biology. He is well known for his work on cell-membrane physiology, particularly the biosynthesis of many cell-surface proteins, and on the cloning and functional analysis of several cell-surface receptor proteins, such as the erythropoietin and TGF–β receptors. His laboratory also studies long noncoding RNAs and microRNAs that regulate the development and function of hematopoietic cells and adipocytes. Dr. Lodish teaches undergraduate and graduate courses in cell biology and biotechnology.

Headshot of Arnold Berk

Arnold Berk

ARNOLD BERK holds the UCLA Presidential Chair in Molecular Cell Biology in the Department of Microbiology, Immunology, and Molecular Genetics and is a member of the Molecular Biology Institute at the University of California, Los Angeles. Dr. Berk is also a fellow of the American Academy of Arts and Sciences. He is one of the discoverers of RNA splicing and of mechanisms for gene control in viruses. His laboratory studies the molecular interactions that regulate transcription initiation in mammalian cells, focusing in particular on adenovirus regulatory proteins. He teaches an advanced undergraduate course in cell biology of the nucleus and a graduate course in the biochemistry of gene expression.

Headshot of Chris A. Kaiser

Chris A. Kaiser

CHRIS A. KAISER is the Amgen Inc. Professor in the Department of Biology at the Massachusetts Institute of Technology. He is also a former Department Head and former Provost at MIT. His laboratory uses genetic and cell biological methods to understand how newly synthesized membrane and secretory proteins are folded and stored in the compartments of the secretory pathway. Dr. Kaiser is recognized as a top educator at MIT, where he has taught genetics to undergraduate and graduate students for many years.

Headshot of Monty Krieger

Monty Krieger

MONTY KRIEGER is the Whitehead Professor in the Department of Biology at the Massachusetts Institute of Technology and a Senior Associate Member of the Broad Institute of MIT and Harvard. Dr. Krieger is also a member of the National Academy of Sciences. For his innovative teaching of undergraduate biology and human physiology as well as graduate cell biology courses, he has received numerous awards. His laboratory has made contributions to our understanding of membrane trafficking through the Golgi apparatus and has cloned and characterized receptor proteins important for pathogen recognition and the movement of cholesterol into and out of cells, including the HDL receptor.

Headshot of Anthony Bretscher

Anthony Bretscher

ANTHONY BRETSCHER is Professor of Cell Biology at Cornell University and a member of the Weill Institute for Cell and Molecular Biology. His laboratory is well known for identifying and characterizing new components of the actin cytoskeleton and elucidating their biological functions in relation to cell polarity and membrane traffic. For this work, his laboratory exploits biochemical, genetic, and cell biological approaches in two model systems, vertebrate epithelial cells and the budding yeast. He is a fellow of the American Academy of Arts and Sciences. Dr. Bretscher teaches cell biology to undergraduates at Cornell University.

Headshot of Hidde Ploegh

Hidde Ploegh

HIDDE PLOEGH is a senior investigator in the Program of Cellular and Molecular Medicine at Boston Children’s Hospital, where he studies the biochemistry of the immune system. A Member of the National Academy of Science and the American Academy of Arts and Sciences, he is one of the world’s leading researchers in the molecular understanding of immune system cells and the mechanisms by which viruses evade detection by the immune system. Prior to his current position he was a professor at the Massachusetts Institute of Technology and Harvard Medical School, where he taught immunology and cell biology.

Headshot of Kelsey C. Martin

Kelsey C. Martin

KELSEY C. MARTIN is Professor of Biological Chemistry and Psychiatry and Dean of the David Geffen School of Medicine at the University of California, Los Angeles. She is the former Chair of the Biological Chemistry Department. Her laboratory studies the ways in which experience changes connections between neurons in the brain to store long-term memories—a process known as synaptic plasticity. She has made important contributions to elucidating the molecular and cell biological mechanisms that underlie this process. Dr. Martin teaches basic principles of neuroscience to undergraduates, graduate students, dental students, and medical students.

Headshot of Michael Yaffe

Michael Yaffe

MICHAEL B. YAFFE is the David H. Koch Professor of Science in the Departments of Biology and Biological Engineering at the Massachusetts Institute of Technology and a Senior Associate Member of the Broad Institute of MIT and Harvard. He is also the Academic Editor-in-Chief of the journal Science Signaling. His laboratory studies the cellular response to stress and injury, and is well known for the discovery and characterization of modular protein domains and protein kinases that form molecular signaling circuits. Dr. Yaffe teaches undergraduate biochemistry and graduate cell biology courses, for which he has received numerous awards. He also instructs medical students and residents in the intensive care unit at the Beth Israel Deaconess Medical Center, where he is an attending physician.

Headshot of Angelika Amon

Angelika Amon

ANGELIKA AMON is Professor of Biology at the Massachusetts Institute of Technology, a member of the Koch Institute for Integrative Cancer Research, and Investigator at the Howard Hughes Medical Institute. She is also a member of the National Academy of Sciences. Her laboratory studies the molecular mechanisms that govern chromosome segregation during mitosis and meiosis and the consequences—aneuploidy—when these mechanisms fail during normal cell proliferation and cancer development. Dr. Amon teaches undergraduate and graduate courses in cell biology and genetics.

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Harvey Lodish; Arnold Berk; Chris A. Kaiser; Monty Krieger; Anthony Bretscher; Hidde Ploegh; Kelsey C. Martin; Michael Yaffe; Angelika Amon | Ninth Edition | ©2021 | ISBN:9781319365516

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